Endocrine Abstracts

Background: Bisphosphonates are capable of suppressing parathormone (PTH)-mediated bone resorption and can be used as an adjunct treatment in acute hypercalcemia. We investigated the effects of oral alendronate on bone mineral density (BMD) and biochemical markers of calcium and bone metabolism in patients with primary hyperparathyroidism (PHPT).Methods: Twenty-six patients aged 58.5±13.9 years with confirmed PHPT were treated with alendronate (70 m...

It is known that acromegaly may be associated with headache as a significant co-morbidity. Amongst all acromegaly headache patients, there is a unique group with specific types of severe headache that fail to improve despite acromegaly therapy and are resistant to conventional analgesics, however, immediately respond to subcutaneous short-acting (SA) somatostatin analogue (SSA) treatment. We have surveyed 8 tertiary specialist UK centres and identified 18 patients (6 females) ...